Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 127
interventional 106
Observational 18
Registry 3

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Other 20
Procedure 19
Drug 18
Device 14
Drug|placebo 10
Drug|Procedure 4
Behavioral 3
Device|Procedure 3
Device|Other 2
Diagnostic Test 2
Other|Procedure 2
Behavioral|Procedure 1
Biological|placebo 1
Combination Product 1
Combination Product|Other 1
Device|Drug 1
Device|placebo 1
Drug|Other 1
Drug|placebo|Procedure 1
Other|placebo 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 49
NA 9
Korea, Republic of 5
Sweden 5
Canada 4
France 4
Netherlands 4
Norway 3
Belgium 2
Saudi Arabia 2
Turkey 2
Australia 1
Austria|Belgium|Bulgaria|Czechia|France|Georgia|Italy|Latvia|Netherlands|Romania|Serbia|Slovakia|Spain|United Kingdom 1
Brazil 1
China 1
Czechia|Denmark|France|Sweden 1
Denmark|France|Germany|Norway|Sweden 1
Egypt 1
Finland 1
India 1
Lebanon 1
Pakistan 1
Russian Federation 1
Singapore 1
Spain 1
Thailand 1
United Kingdom 1
United States|Belgium|Canada|Germany|Italy|Spain|Sweden|Turkey 1

Sites per Study

Site_count Study_Count
1 72
2 11
3 3
4 4
5 1
6 1
12 1
17 1
18 1
23 3
25 1
29 1
31 1
33 1
38 1
52 1
56 1
57 1

Phase

Phase Study_Count
N/A 64
Phase 3 13
Phase 2 10
Phase 4 10
Phase 2/Phase 3 4
Phase 1 2
Phase 1/Phase 2 2
Early Phase 1 1

Number of Arms

Number_of_Arms Count_of_Studies
1 9
2 77
3 13
4 1
NA 6

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 10 10.00 18 18.0 44.00 12.00 54.0000 22.00
1st Qu. 10 43.75 27 58.5 80.50 66.00 74.0000 41.75
Median 10 96.50 36 99.0 120.00 92.00 100.0000 73.00
Mean 10 119.00 36 99.0 146.80 94.25 193.4615 86.70
3rd Qu. 10 142.50 45 139.5 141.75 120.25 276.0000 126.25
Max. 10 500.00 54 180.0 502.00 181.00 494.0000 200.00

Trial Group Type

group_type Group_Count
Experimental 92
Active Comparator 74
Placebo Comparator 19
Other 11
No Intervention 7
NA 6
Sham Comparator 3

Intervention Model

intervention_model Study_Count
Parallel Assignment 84
Single Group Assignment 12
Crossover Assignment 7
Factorial Assignment 2
NA 1

Primary Purpose

primary_purpose Study_Count
Treatment 89
Supportive Care 5
Basic Science 4
Prevention 3
Device Feasibility 1
Diagnostic 1
Health Services Research 1
Other 1
Screening 1

Observational Studies

Studies by Country

Country Study_Count
United States 6
Egypt 2
France 2
Netherlands 2
Turkey 2
Korea, Republic of 1
NA 1
Switzerland 1
United States|Korea, Republic of 1

Sites per Study

Site_count Study_Count
1 15
3 2
25 1

Enrollment Metrics

Measure Observational
Min 6.0000
1st Qu 42.5000
Median 101.5000
Mean 259.8889
3rd Qu 162.0000
Max 2000.0000

Observation Model

observational_model Study_Count
Cohort 11
Case-Control 2
Case-Only 2
Other 2
Case Control 1

Time Perspective

time_perspective Study_Count
Prospective 12
Retrospective 4
Cross-Sectional 1
Other 1

Registries

Studies by Country

Country Study_Count
Korea, Republic of 2
NA 1

Sites per Study

Site_count Study_Count
1 2
4 1

Enrollment Metrics

Measure Registries
Min 40.0000
1st Qu 170.0000
Median 300.0000
Mean 446.6667
3rd Qu 650.0000
Max 1000.0000

Registry Model

observational_model Study_Count
Case-Only 2
Cohort 1

Time Perspective

time_perspective Study_Count
Prospective 3

Follow-up

target_duration Study_Count
3 Months 1
52 Weeks 1
6 Months 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03382821 Comparative Trial Via Tranforaminal Approach Versus Epidural Catheter Via Interlaminar Approach https://ClinicalTrials.gov/show/NCT03382821 Active, not recruiting University of Utah 2020-04-15
NCT03372161 Corticosteroid Lumbar Epidural Analgesia for Radiculopathy https://ClinicalTrials.gov/show/NCT03372161 Recruiting Scilex Pharmaceuticals, Inc. 2020-07-01
NCT03821350 The Effect of Comorbid Psychiatric Conditions on Results of Transforaminal Epidural Steroid Injection https://ClinicalTrials.gov/show/NCT03821350 Completed Hitit University 2014-12-30
NCT03362567 Sustained Natural Apophyseal Glides and Mechanical Cervical Traction in the Management of Cervical Radiculopathy https://ClinicalTrials.gov/show/NCT03362567 Completed Obafemi Awolowo University 2017-04-15
NCT03341182 The Effects of Use of Mirror Image on Radiation Exposure During Fluoroscopically Guided Transforaminal Epidural Injection https://ClinicalTrials.gov/show/NCT03341182 Completed Yonsei University 2018-08-21
NCT03328351 Effect of Manual Therapy on Sensory Features in Patients With Cervical Radiculopathy https://ClinicalTrials.gov/show/NCT03328351 Completed Dammam University 2017-08-24
NCT03327272 Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion https://ClinicalTrials.gov/show/NCT03327272 Recruiting Rush University Medical Center 2020-12-31
NCT03308136 The Effect of Local Anesthetic Injection Depth on Procedural Pain and Discomfort During Fluoroscopically Guided Lumbar Transforaminal Epidural Injections https://ClinicalTrials.gov/show/NCT03308136 Completed Yonsei University 2018-02-28
NCT03286946 Detection of Intravascular Injection Between Blunt and Sharp Needles During Cervical Transforaminal Epidural Block. https://ClinicalTrials.gov/show/NCT03286946 Completed Kyungpook National University Hospital 2017-07-01
NCT03201393 Twice Daily Oral ALLOD-2 vs. Placebo in the Treatment of Chronic Low Back Pain (ANODYNE-4) https://ClinicalTrials.gov/show/NCT03201393 Completed Allodynic Therapeutics, LLC 2018-07-26
NCT03185442 Cerebral Effects of Pulsed Radiofrequency on the Lumbar Dorsal Root Ganglion With Functional Magnetic Resonance Imaging. https://ClinicalTrials.gov/show/NCT03185442 Recruiting Universitair Ziekenhuis Brussel 2019-07-15
NCT03133845 Shaping Anesthetic Techniques to Reduce Post-operative Delirium https://ClinicalTrials.gov/show/NCT03133845 Completed Johns Hopkins University 2020-05-25
NCT03127826 Validation of the STarT Back Screening Tool in the Military https://ClinicalTrials.gov/show/NCT03127826 Recruiting Brooke Army Medical Center 2021-01-31
NCT03127137 Do Cervical Interlaminar Epidural Steroid Injections With Low-dose Lidocaine Cause Transient Objective Upper Extremity Weakness? A Prospective Randomized Controlled Trial https://ClinicalTrials.gov/show/NCT03127137 Recruiting Northwestern University 2021-12-31
NCT03111277 MR Guided Focused Ultrasound for Treatment of Neuropathic Pain https://ClinicalTrials.gov/show/NCT03111277 Recruiting University of Maryland, Baltimore 2020-05-15
NCT03062657 An Investigation of the Metal Concentration in Patients Implanted With the PRESTIGE LPâ„¢ Cervical Disc at Two Contiguous Levels in the Cervical Spine https://ClinicalTrials.gov/show/NCT03062657 Recruiting Medtronic Spinal and Biologics 2021-06-30
NCT03060434 Pentoxifylline and Lumbar Radiculopathy https://ClinicalTrials.gov/show/NCT03060434 Active, not recruiting St Joseph University, Beirut, Lebanon 2020-12-01
NCT03036007 Physiotherapy After Anterior Cervical Spine Surgery https://ClinicalTrials.gov/show/NCT03036007 Recruiting Linkoeping University 2022-12-31
NCT03023696 Can Prophylactic Foraminotomy Prevent C5 Palsy https://ClinicalTrials.gov/show/NCT03023696 Recruiting The Cleveland Clinic 2020-12-31
NCT02939482 A Study Comparison of Clinical Outcome After Different Rate of Infusion in Caudal Epidural Steroid Injection https://ClinicalTrials.gov/show/NCT02939482 Completed Navamindradhiraj University 2018-08-02
NCT02935608 Study to Evaluate the Efficacy and Safety of BIIB074 in Neuropathic Pain From Lumbosacral Radiculopathy https://ClinicalTrials.gov/show/NCT02935608 Completed Biogen 2018-08-06
NCT02644421 Clinical Trial to Evaluate the Safety and Analgesic Efficacy of VVZ-149 in Lumbar Radiculopathy (Sciatica) https://ClinicalTrials.gov/show/NCT02644421 Completed Brigham and Women’s Hospital 2017-07-31
NCT02630732 Back School or Brain School for Patients Undergoing Surgery for Lumbar Radiculopathy? https://ClinicalTrials.gov/show/NCT02630732 Active, not recruiting Universitair Ziekenhuis Brussel 2021-06-30
NCT02618278 Physiotherapy for Sciatica; Is Earlier Better? https://ClinicalTrials.gov/show/NCT02618278 Completed Sheffield Teaching Hospitals NHS Foundation Trust 2016-11-30
NCT02531711 Chronic Lumbosacral Radiculopathy: Impact of an Analgesic Dietary Intervention on Pain & Function https://ClinicalTrials.gov/show/NCT02531711 Recruiting University of North Carolina, Chapel Hill 2019-12-30
NCT02508805 Safety and Efficacy of Neuromultivit in Treatment of Vertebrogenic Radiculopathy https://ClinicalTrials.gov/show/NCT02508805 Completed Bausch Health Americas, Inc. 2015-09-30
NCT03386149 Clinical Research on the Efficacy of Bosinji on Herniated Intervertebral Disc of Lumbar Spine https://ClinicalTrials.gov/show/NCT03386149 Completed Kyunghee University Medical Center 2019-12-27
NCT02265848 High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System https://ClinicalTrials.gov/show/NCT02265848 Completed The Center for Clinical Research, Winston-Salem, NC 2015-01-31
NCT02217280 Dispersal Pattern for Spine Injections (Gadolinium Contrast) https://ClinicalTrials.gov/show/NCT02217280 Completed University of Missouri-Columbia 2016-03-31
NCT02196129 Immediate Pain Relieving Effects of Sinbaro-3 for Low Back Pain https://ClinicalTrials.gov/show/NCT02196129 Completed Jaseng Hospital of Korean Medicine 2014-10-31
NCT02130258 Somatosensory Profiling in Radicular Pain Patients And it’s Correlation With Treatment Outcome https://ClinicalTrials.gov/show/NCT02130258 Completed Massachusetts General Hospital 2016-12-31
NCT02095197 C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain https://ClinicalTrials.gov/show/NCT02095197 Completed Northwestern University 2016-07-31
NCT02081456 Soft Tissue Mobilization Versus Therapeutic Ultrasound for Subjects With Neck and Arm Pain https://ClinicalTrials.gov/show/NCT02081456 Completed University of Nevada, Las Vegas 2012-06-30
NCT01303354 Lumbar Transforaminal Epidural Dexamethasone https://ClinicalTrials.gov/show/NCT01303354 Completed Ahadian, Farshad M., M.D. 2010-06-30
NCT02030626 Comparison of the Efficacy of rTMS and tDCS of the Motor Cortex in Patients With Chronic Neuropathic Pain https://ClinicalTrials.gov/show/NCT02030626 Completed Hospital Ambroise Paré Paris 2015-01-31
NCT01944150 Association of Transcutaneous Electrical Nerve Stimulation and Hypnosis https://ClinicalTrials.gov/show/NCT01944150 Completed Assistance Publique - Hôpitaux de Paris 2017-02-28
NCT01917825 A Study of the Pharmacokinetics, Safety, and Preliminary Efficacy of MDT-15 in Subjects With Lumbosacral Radiculopathy https://ClinicalTrials.gov/show/NCT01917825 Completed Medtronic Spinal and Biologics 2015-10-31
NCT01911013 A Study of Korean Society of Spine Surgery on the Outcomes of Anterior Cervical Discectomy and Fusion https://ClinicalTrials.gov/show/NCT01911013 Active, not recruiting Seoul National University Hospital 2017-09-01
NCT01905930 Post-Approval Clinical Trial of the PCM® Cervical Disc https://ClinicalTrials.gov/show/NCT01905930 Completed NuVasive 2015-04-30
NCT01831271 Neck-specific Training or Prescribed Physical Activity for Patients With Cervical Radiculopathy https://ClinicalTrials.gov/show/NCT01831271 Completed Karolinska University Hospital 2016-01-31
NCT01760317 Two Different Approaches During Fluoroscopically Guided Interlaminar Lumbar Epidural Steroid Injection https://ClinicalTrials.gov/show/NCT01760317 Completed Chicago Anesthesia Pain Specialists 2013-05-31
NCT01655849 Phase 2 Efficacy Trial of Z160 in Lumbosacral Radiculopathy https://ClinicalTrials.gov/show/NCT01655849 Completed Zalicus 2013-10-31
NCT01609374 Restore CLINICAL TRIAL https://ClinicalTrials.gov/show/NCT01609374 Active, not recruiting Spinal Kinetics 2019-12-31
NCT01561027 Crossover Study of CNV1014802 in Subjects With Neuropathic Pain From Lumbosacral Radiculopathy https://ClinicalTrials.gov/show/NCT01561027 Completed Biogen 2012-06-30
NCT01547611 Outcome of Physiotherapy After Surgery for Cervical Disc Disease: a Prospective Multi-Centre Trial https://ClinicalTrials.gov/show/NCT01547611 Completed Linkoeping University 2014-12-31
NCT01500044 Effect of Mobilizations and Exercises Targeting the Opening of Intervertebral Foramens Following Cervical Radiculopathy https://ClinicalTrials.gov/show/NCT01500044 Completed Laval University 2013-06-30
NCT01495923 Steroids Versus Gabapentin https://ClinicalTrials.gov/show/NCT01495923 Completed Johns Hopkins University 2014-06-30
NCT01367860 Percutaneous Diskectomy SpineJet x Open Microdiskectomy in Treatment of Lumbar Radiculopathy https://ClinicalTrials.gov/show/NCT01367860 Completed University of Sao Paulo 2012-04-30
NCT01335646 Surgery Versus Standardized Non-operative Care for the Treatment of Lumbar Disc Herniations: A Canadian Trial https://ClinicalTrials.gov/show/NCT01335646 Completed The London Spine Centre 2018-08-31
NCT04276519 Position-Induced Opening of the Intervertebral Foramen is Efficient to Treat an Acute Lumbosacral Radiculopathy Caused by Disc Herniation https://ClinicalTrials.gov/show/NCT04276519 Completed General Hospital Sveti Duh 2016-07-01
NCT04238793 Single Ascending Doses Study of KLS-2031 in Subjects With Neuropathic Pain From Lumbosacral Radiculopathy https://ClinicalTrials.gov/show/NCT04238793 Recruiting Kolon Life Science 2021-11-30
NCT04215757 Low Dose Lignocaine Injections as a Treatment Option for Acute Lumbosacral Radiculopathy https://ClinicalTrials.gov/show/NCT04215757 Recruiting All India Institute of Medical Sciences, Rishikesh 2020-01-15
NCT04212949 The Effect of Transcranial Magnetic Stimulation Therapy in Patients With Lumbar Radiculopathy https://ClinicalTrials.gov/show/NCT04212949 Recruiting Marmara University 2020-11-08
NCT04177849 Örebro Multicenter Study on Operative Treatment of Cervical Radiculopathy https://ClinicalTrials.gov/show/NCT04177849 Recruiting Region Örebro County 2022-01-31
NCT04169477 Comparison of Two Modes of Transcutaneous Electrical Nerve Stimulation (TENS) in Chronic Neuropathic Radiculalgia https://ClinicalTrials.gov/show/NCT04169477 Recruiting Lille Catholic University 2021-06-30
NCT04163939 Collar Use for Cervical Radicular Pain https://ClinicalTrials.gov/show/NCT04163939 Recruiting Rhode Island Hospital 2020-08-31
NCT04144972 Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain https://ClinicalTrials.gov/show/NCT04144972 Recruiting University of California, San Francisco 2024-10-24
NCT04042948 Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery https://ClinicalTrials.gov/show/NCT04042948 Recruiting Peking University Third Hospital 2020-05-28
NCT03979443 Finnish Trial on Practices of Anterior Cervical Decompression (FACADE) Comparing Outpatient vs. Inpatient Care https://ClinicalTrials.gov/show/NCT03979443 Recruiting Helsinki University Central Hospital 2021-12-31
NCT03952377 Safety and Efficacy of SX600 Administered by Lumbosacral Transforaminal Epidural Injection for Radicular Pain https://ClinicalTrials.gov/show/NCT03952377 Recruiting SpineThera Australia PTY LTD 2020-06-30
NCT03924791 Transforaminal Epidural Injection in Acute Sciatica https://ClinicalTrials.gov/show/NCT03924791 Recruiting Leiden University Medical Center 2020-12-31
NCT03894943 Quantitative Sensory Testing and PET/CT Scanning in Assessment of Surgical Outcome for Lumbar Disc Herniation https://ClinicalTrials.gov/show/NCT03894943 Completed Spine Centre of Southern Denmark 2018-11-30
NCT03842072 The Collar Post Anterior Cervical Spine Surgery Study https://ClinicalTrials.gov/show/NCT03842072 Recruiting St. Michael’s Hospital, Toronto 2020-07-01
NCT03835182 Efficacy of Ultrasound Versus Short Wave Diathermy in the Treatment of a Slipped Disc of the Lower Back https://ClinicalTrials.gov/show/NCT03835182 Recruiting Baskent University 2020-12-31
NCT03801356 Threshold Response of Lumbar Selective Nerve Root Block in Predicting Good Outcome Following Lumbar Foraminotomy https://ClinicalTrials.gov/show/NCT03801356 Recruiting The Cleveland Clinic 2020-08-23
NCT03786432 Prospective Study of Fusion Rates Using Spira-C Device for Anterior Cervical Discectomy and Fusion Surgery https://ClinicalTrials.gov/show/NCT03786432 Recruiting William Beaumont Hospitals 2020-12-31
NCT03733626 Clinical Outcomes Associated With the Use of ViviGen® for the Treatment of Lumbar Degenerative Disc Disease https://ClinicalTrials.gov/show/NCT03733626 Active, not recruiting William Beaumont Hospitals 2022-11-01
NCT03727100 Treatment of Pain Associated With Lumbosacral Radiculopathy in Adults https://ClinicalTrials.gov/show/NCT03727100 Active, not recruiting Sollis Therapeutics, Inc. 2019-12-14
NCT03674619 Cervical Radiculopathy Trial https://ClinicalTrials.gov/show/NCT03674619 Recruiting Oslo University Hospital 2021-10-31
NCT03636009 Concurrent Treatment for Patients With Cervical Radiculopathy https://ClinicalTrials.gov/show/NCT03636009 Recruiting University of Indianapolis 2019-07-31
NCT03621878 Effect of Neural Mobilization on Lumbosacral Radiculopathy Patients With Peripheral Sensitization https://ClinicalTrials.gov/show/NCT03621878 Completed Imam Abdulrahman Bin Faisal University 2017-11-28
NCT03620864 Neurodynamic Intervention for Lumbar Radiculopathy https://ClinicalTrials.gov/show/NCT03620864 Completed Universidad Rey Juan Carlos 2018-10-03
NCT03514277 A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief https://ClinicalTrials.gov/show/NCT03514277 Recruiting Virtua Health, Inc. 2019-12-31
NCT03428139 Alpha Lipoic Acid and Chronic Lumbosacral Radicular Pain https://ClinicalTrials.gov/show/NCT03428139 Completed Assiut University 2017-03-03
NCT03419312 PET Patterns, Biomarkers and Outcome in Burst SCS Treated FBSS Patients https://ClinicalTrials.gov/show/NCT03419312 Active, not recruiting Uppsala University 2021-06-30
NCT01144923 Conservative Therapy Versus Epidural Steroids for Cervical Radiculopathy https://ClinicalTrials.gov/show/NCT01144923 Completed Johns Hopkins University 2013-11-30
NCT01110057 Efficacy Study in Lumbosacral Radiculopathy https://ClinicalTrials.gov/show/NCT01110057 Completed GlaxoSmithKline 2010-08-23
NCT01073995 The Effectiveness of Selective Nerve Root Injections in Preventing the Need for Surgery https://ClinicalTrials.gov/show/NCT01073995 Completed Horizon Health Network 2015-11-30
NCT01061697 Pregabalin and Radicular Pain Study (PARPS) https://ClinicalTrials.gov/show/NCT01061697 Completed Singapore General Hospital 2010-03-31
NCT01052571 Evaluation of the Effectiveness of Transforaminal Epidural Injections in Lumbar Disc Herniation or Radiculitis https://ClinicalTrials.gov/show/NCT01052571 Completed Pain Management Center of Paducah 2012-01-31
NCT00991237 PRF Treatment for Patients With Chronic Lumbosacral Radicular Pain Compared to Conventional Medical Management https://ClinicalTrials.gov/show/NCT00991237 Completed Maastricht University Medical Center 2012-12-31
NCT00979108 The Value of Traction in the Treatment of Cervical Radiculopathy https://ClinicalTrials.gov/show/NCT00979108 Completed Intermountain Health Care, Inc. 2012-03-31
NCT00942227 The Value of Traction in Treatment of Lumbar Radiculopathy https://ClinicalTrials.gov/show/NCT00942227 Completed Intermountain Health Care, Inc. 2012-12-31
NCT00934284 Effectiveness Study of Physical Therapy as an Adjunct to a Lumbar Therapeutic Selective Nerve Root Block https://ClinicalTrials.gov/show/NCT00934284 Completed University of Utah 2008-02-29
NCT00908375 Efficacy of Pregabalin in Patients With Radicular Pain https://ClinicalTrials.gov/show/NCT00908375 Completed Northwestern University 2012-09-30
NCT00894972 Rehabilitation Following Lumbar Disc Surgery https://ClinicalTrials.gov/show/NCT00894972 Completed University of Utah 2012-04-30
NCT00826124 Does Magnetic Resonance Imaging (MRI) Improve Interventional Outcomes for Lumbosacral Radiculopathy? https://ClinicalTrials.gov/show/NCT00826124 Completed Johns Hopkins University 2011-02-28
NCT04427423 Positional Distraction and Stabilization Exercises in Adults With Lumbar Radiculopathy. https://ClinicalTrials.gov/show/NCT04427423 Recruiting Dow University of Health Sciences 2020-12-31
NCT01842126 Phase 1 Subcutaneous Single and Multiple Ascending Dose Study of BG00010 (Neublastin) https://ClinicalTrials.gov/show/NCT01842126 Completed Biogen 2014-08-31
NCT04022798 Management of LBP With Radiculopathy. https://ClinicalTrials.gov/show/NCT04022798 Recruiting University of Tabuk 2019-10-30
NCT01873404 BG00010 (Neublastin) Phase 2 Multiple Dose Adaptive Design in Participants With Painful Lumbar Radiculopathy https://ClinicalTrials.gov/show/NCT01873404 Completed Biogen 2015-03-31
NCT00735176 The Norwegian Cervical Arthroplasty Trial https://ClinicalTrials.gov/show/NCT00735176 Completed Norwegian University of Science and Technology 2017-08-31
NCT00733096 A 3-arm Multi-center, Randomized Controlled Study Comparing Transforaminal Corticosteroid, Transforaminal Etanercept and Transforaminal Saline for Lumbosacral Radiculopathy https://ClinicalTrials.gov/show/NCT00733096 Completed Johns Hopkins University 2011-03-31
NCT00637156 Study of the Safety and Effectiveness of the Artificial Cervical Disc - Low Profile Device at Two Adjacent Levels https://ClinicalTrials.gov/show/NCT00637156 Completed Medtronic Spinal and Biologics 2011-01-31
NCT00578812 PCM Cervical Disc System https://ClinicalTrials.gov/show/NCT00578812 Completed NuVasive 2010-03-31
NCT00554528 Arthroplasty Versus Fusion in Anterior Cervical Surgery: Prospective Study of the Impact on the Adjacent Level https://ClinicalTrials.gov/show/NCT00554528 Completed Centre Hospitalier Universitaire de Nice 2012-05-31
NCT00440856 Presentation of Lumbar Disc and Reduction of Symptoms https://ClinicalTrials.gov/show/NCT00440856 Completed St George’s, University of London 2008-04-30
NCT00437190 Pivotal IDE Study of the BRYAN(R) Cervical Disc Prosthesis in the Treatment of DDD Versus ACDF https://ClinicalTrials.gov/show/NCT00437190 Completed Medtronic Spinal and Biologics 2006-12-31
NCT00416117 Manual Physical Therapy and Exercise for Mechanical Neck Disorders https://ClinicalTrials.gov/show/NCT00416117 Completed Brooke Army Medical Center NA
NCT00384007 A Randomized Trial Comparing SpineJet® Hydrodiscectomy to Open Lumbar Microdiscectomy for Treatment of Lumbar Radiculopathy Due to Disc Herniation https://ClinicalTrials.gov/show/NCT00384007 Completed Pinnacle Pain Medicine NA
NCT00344890 Safety Study of Preservon-Treated Bone Implants for Cervical Fusion in the Treatment of Cervical Radiculopathy or Myelopathy https://ClinicalTrials.gov/show/NCT00344890 Completed LifeNet Health 2011-12-31
NCT00159705 Trial of Efficacy and Safety of Pregabalin in Subjects With Neuropathic Pain Associated With Lumbo-Sacral Radiculopathy https://ClinicalTrials.gov/show/NCT00159705 Completed Pfizer NA
NCT00129714 Westeinde Brachialgia Study https://ClinicalTrials.gov/show/NCT00129714 Completed Medical Center Haaglanden 2007-04-30
NCT00120120 Study to Evaluate the Efficacy and Safety of Lenalidomide in the Treatment of Painful Lumbar Radiculopathy https://ClinicalTrials.gov/show/NCT00120120 Completed Celgene 2007-10-31
NCT00009672 Pain Treatment for Sciatica https://ClinicalTrials.gov/show/NCT00009672 Completed National Institutes of Health Clinical Center (CC) NA
NCT00395798 Effect of Cervical Collar in Cervical Radicular Pain. https://ClinicalTrials.gov/show/NCT00395798 Completed Oslo University Hospital NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03309371 DISCOGEL ®: Evaluation of the Procedure DISCOGEL ® in Lumbar Radiculopathy on Slipped Disc https://ClinicalTrials.gov/show/NCT03309371 Completed Groupe Hospitalier Paris Saint Joseph 2016-08-31
NCT03303300 The Five-repetition Sit-to-stand Test for Lower Back Pain or Radiculopathy https://ClinicalTrials.gov/show/NCT03303300 Completed Bergman Clinics 2017-12-01
NCT02761928 Investigation of Hypermobility, Biomarkers, and Pain Generators in Chronic Pain Patients https://ClinicalTrials.gov/show/NCT02761928 Active, not recruiting The University of Texas Health Science Center, Houston 2025-12-31
NCT02403453 RHINEâ„¢ Cervical Disc Clinical Study: A Prospective Observational Study for Patients Requiring 1-2 Level C-spine Surgery https://ClinicalTrials.gov/show/NCT02403453 Enrolling by invitation K2M, Inc. 2026-08-31
NCT02329951 Predictive Factors for LBP Interventional Treatment Outcomes https://ClinicalTrials.gov/show/NCT02329951 Recruiting Johns Hopkins University 2020-07-31
NCT02064790 Comparison of Gabapentin and Pregabalin for Radicular Pain https://ClinicalTrials.gov/show/NCT02064790 Completed Emory University 2015-12-31
NCT02025283 Efficacy of Radiofrequency Nucleoplasty and Targeted Disc Decompression in Lumbar Radiculopathy https://ClinicalTrials.gov/show/NCT02025283 Completed Ankara University 2012-12-31
NCT04324281 Myth of Double Crush Syndrome in Median Nerve https://ClinicalTrials.gov/show/NCT04324281 Completed Cairo University 2020-03-07
NCT04320043 Adjacent Segment Disease After Anterior Cervical Decompression Surgery https://ClinicalTrials.gov/show/NCT04320043 Recruiting Zuyderland Medisch Centrum 2020-07-01
NCT04305509 Outcomes After Chiropractic Spinal Manipulative Therapy With Lumbar Disc Herniation and Radiculopathy https://ClinicalTrials.gov/show/NCT04305509 Recruiting Balgrist University Hospital 2020-12-31
NCT03959098 Effectiveness and Safety of Korean Medicine Treatment for Cervical Disc Herniation https://ClinicalTrials.gov/show/NCT03959098 Recruiting Jaseng Medical Foundation 2020-12-31
NCT03950349 FUSION EVALUATION AFTER ANTERIOR CERVICAL DISCECTOMY AND FUSION WITH STAND ALONE LOCKING CAGE WITH BLADE HRCC® https://ClinicalTrials.gov/show/NCT03950349 Recruiting CHU de Reims 2019-07-01
NCT03890315 Evaluation of Neuropathic Pain in the Context of Clinical Symptoms, Quantitative Sensory Tests and Imaging With FMRI https://ClinicalTrials.gov/show/NCT03890315 Completed Ege University 2020-04-07
NCT03776318 Long-Term Follow-up Safety of Clonidine Micropellets https://ClinicalTrials.gov/show/NCT03776318 Enrolling by invitation Sollis Therapeutics, Inc. 2021-11-30
NCT03532230 Cost Effectiveness of OMT for Chronic Low Back Pain https://ClinicalTrials.gov/show/NCT03532230 Completed Rowan University 2020-02-28
NCT00984672 Evaluation of Radiculitis Following Use of Bone Morphogenetic Protein-2 for Interbody Arthrodesis in Spinal Surgery https://ClinicalTrials.gov/show/NCT00984672 Active, not recruiting Mayo Clinic 2016-12-31
NCT04320836 Non-organic Signs to Predict Outcomes for Neck Pain https://ClinicalTrials.gov/show/NCT04320836 Recruiting Johns Hopkins University 2022-06-30
NCT04279340 Correlation Between Chronic Neck Pain and Shoulder Proprioception Among Patients With Cervical Radiculopathy https://ClinicalTrials.gov/show/NCT04279340 Completed Cairo University 2019-04-05

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT02403687 Prospective Analgesic Compound Efficacy (PACE) Study https://ClinicalTrials.gov/show/NCT02403687 Completed Express Specialty Pharmacy 2016-12-31
NCT03750591 Observational Study on Effectiveness and Safety of Integrative Korean Medicine Treatment for Inpatients With Sciatica Due to Lumbar Intervertebral Disc Herniation https://ClinicalTrials.gov/show/NCT03750591 Completed Jaseng Medical Foundation 2019-05-10
NCT03571503 The Effectiveness of Doin (Conduction Exercise) of the Pelvic Joint for HLD With Radiating Leg Pain https://ClinicalTrials.gov/show/NCT03571503 Completed Jaseng Medical Foundation 2019-07-04